Należy zachować ostrożność u osób z zaburzeniami czynności układu oddechowego, ponieważ leki nasenne mogą hamować czynność ośrodka oddechowego.Nedsatt konsentrasjon av zopiklon. Basert på data fra andre kraftige induktorer av CYP3A4 må gentleman regne med at konsentrasjonen av zopiklon kan synke med i størrelsesorden inntil 80 %.
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